ISOSORBIDE DINITRATE MIXTURE

A crystalline solid. May be toxic by ingestion. Used to make pharmaceuticals. Used as a heart drug.

• Highly Flammable

Highly flammable. Slightly soluble in water.

Flammable/combustible material. May be ignited by friction, heat, sparks or flames. Some may burn rapidly with flare burning effect. Powders, dusts, shavings, borings, turnings or cuttings may explode or burn with explosive violence. Substance may be transported in a molten form at a temperature that may be above its flash point. May re-ignite after fire is extinguished. (ERG, 2008)

Fire may produce irritating and/or toxic gases. Contact may cause burns to skin and eyes. Contact with molten substance may cause severe burns to skin and eyes. Runoff from fire control may cause pollution. (ERG, 2008)

Nitroalkanes, such as ISOSORBIDE DINITRATE MIXTURE, range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. Nitroalkanes are milder oxidizing agents, but still react violently with reducing agents at higher temperature and pressures. Nitroalkanes react with inorganic bases to form explosive salts. The presence of metal oxides increases the thermal sensitivity of nitroalkanes. Nitroalkanes with more than one nitro group are generally explosive. Nitroalkanes are insoluble in water. This heart drug is detonable when dry, but non-explosive with 30% of water.

• Nitrites, Nitrates, and Nitro Compounds, Organic

Solid streams of water may spread fire. Use water in flooding quantities as fog. Use dry chemical, graphite, or dry earth. (AAR, 2003)

Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. (AAR, 2003)

Avoid breathing dusts, and fumes from burning material. Avoid bodily contact with the material. Wear appropriate chemical protective gloves, boots and goggles. Do not handle broken packages unless wearing appropriate personal protective equipment. Wash away any material which may have contacted the body with copious amounts of water or soap and water. (AAR, 2003)

Move victim to fresh air. Call 911 or emergency medical service. Give artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult. Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush skin or eyes with running water for at least 20 minutes. Removal of solidified molten material from skin requires medical assistance. Keep victim warm and quiet. Ensure that medical personnel are aware of the material(s) involved and take precautions to protect themselves. (ERG, 2008)

• 1,4:3,6-DIANHYDRO-D-GLUCITOL 2,5-DINITRATE
• 1,4:3,6-DIANHYDRO-D-SORBITOL 2,5-DINITRATE
• 1,4:3,6-DIANHYDROSORBITOL 2,5-DINITRATE
• CARDIS
• CARVANIL
• CARVASIN
• CEDOCARD
• CLAODICAL
• COROSORBIDE
• D-ISOSORBIDE DINITRATE
• DINITRATE D'ISOSORBIDE EN MÉLANGE (DOT FRENCH)
• DINITRATO DE ISOSORBIDA, MEZCLA DE (DOT SPANISH)
• DINITROISOSORBIDE
• DINITROSORBIDE
• FLINDIX
• FRANDOL
• FURO[3,2-B]FURAN, D-GLUCITOL DERIV.
• GLUCITOL, 1,4:3,6-DIANHYDRO-, DINITRATE
• GLUCITOL, 1,4:3,6-DIANHYDRO-, DINITRATE, D-
• HARRICAL
• ISDN
• ISODINIT
• ISOKET
• ISOKET RETARD 40
• ISORBID
• ISORDIL
• ISORDIL TEMBIDS
• ISOSORBIDE 2,5-DINITRATE
• ISOSORBIDE DINITRATE
• ISOSORBIDE NITRATE
• KORODIL
• MAYCOR
• NITROSORBID
• NITROSORBIDE
• RESOIDAN
• RIGEDAL
• SORBANGIL
• SORBIDE DINITRATE
• SORBIDE NITRATE
• SORBIDILAT
• SORBIDNITRATE
• SORBITOL, 1,4:3,6-DIANHYDRO-, DINITRATE
• SORBITRATE
• SORBONIT
• SORBOPERCUTEN
• SORQUAD
• TYB 3215
• VASCARDIN
• VASORBATE